Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds.
نویسندگان
چکیده
Current assays for screening new antimalarials need initiators of beta-hematin formation that require laborious preparation, special devices, and substrates. In this study, based on reduction of heme absorption in beta-hematin formation, we developed a simple colorimetric assay using Tween 20 as an initiator and a microplate reader for high-throughput screening of inhibitors of beta-hematin formation.
منابع مشابه
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 51 1 شماره
صفحات -
تاریخ انتشار 2007